Is the link to leaky intestine and autoimmune disease clearer? I believe that it is, Canadian researchers have helped a wonderful review of the intestinal permeability of the British journal Gut.
Dr. JB Medding of Alberta Edmonton (Arrieta, Gut, 2006) in Canada and his colleagues explain how intestines function as barriers when normal, but when abnormally permeable they become autoimmune It will be a source of the origin of the disease. In other words, it is known that if your intestine leaks ("leaky bowel syndrome"), several autoimmune diseases will occur.
The permeability of the intestines (how the intestines are leaking) can be assessed in a way specific to the various parts of the intestine. That is, different areas of the intestine from the stomach to the large intestine are evaluated by specific tests for leakiness and are related to injury and disease in these areas. The area of the leaky intestine is observed prior to the onset of the disease and can be diagnosed as diseases, in particular autoimmune diseases such as celiac disease, diabetes, Crohn's disease, as well as atopic dermatitis, rheumatic disease symptoms as well as irritable bowel syndrome And so on.
The authors propose a consistent new paradigm "three main features ..."
(1) Genetically accepted immune system (mucosal immune system) that allows the host to react abnormally to environmental antigens.
(2) environmental products that cause the disease process.
(3) the ability of environmental agents to interact with the mucosal immune system. The purpose of the epithelial barrier is to keep these two factors separate, and as we measure permeability the function of this barrier, it is natural that increased permeability is a necessary condition for disease development is there. "
What do you mean by ray / term in relation to the concept of Ray Goodst syndrome? Intestines and intestines are considered barriers against foreign proteins such as food and bacteria. If your immune system tends to genetically respond to certain intestinal (or nerve, skin or joint) food proteins and / or bacteria, it is intended to protect you from foreign intruders It may respond to the activation of chemicals It is more leaky and more vulnerable, but also your nerves, skin, and joints.
Leaky gut creates leaky intestines. What consequences will heavily damage your bowel? Food and bacterial proteins work together to damage the gastrointestinal tract and allow toxic protein complexes to pass through the intestines, which are usually thought to be able to tolerate such violations. Once you enter your bloodstream, foreign proteins may initiate abnormal reactions that cause irritation to your brain, nerves, skin and / or joints.
Many things you and I experience are symptoms such as abdominal pain, abdominal distention, gas, diarrhea, headache, neuralgia, skin rash and joint pain. This result is consistent with the results of celiac disease, Crohn's disease and irritable bowel syndrome, multiple sclerosis, migraine, attention deficit, autism, depression, eczema, acne, rheumatoid arthritis, fibromyalgia, diabetes, chronic fatigue And so on.
We have truly personal and professional experiences and those who are keenly interested in this area have explosions of autoimmune diseases under our nose but most physicians and the general public I am losing a connection. Many people are diagnosed with multiple conditions, without anyone, with our gastrointestinal overload connection, together with certain foods that may have caused the majority of these diseases . Food products of all problems have specific food proteins or lectins that are difficult to digest and are toxic to the intestine. In particular, if the food is genetically engineered or modified, the lectin may be more toxic to humans. Please enjoy more about this exciting area, as I continue on the relationship between food, bowels and diseases. As a doctor as your doctor, I would like to help you find the information you need to feel right, even if the doctor is not connected.
References:
Arrieta MC, Bistritz L, Meddings, JB. Recent progress in clinical practice. Change in intestinal permeability. Gut 2006; 55: 1512-1520.
