According to a new study, people suffering from the weekly bones may recover with the help of stem cells derived from pregnant women. In this study, stem cells collected from amniotic fluid from pregnant women were administered in a mouse model, but it is an answer to osteoporosis. Researchers reached this conclusion after reducing the fracture of animals who had suffered from fragile bony structures by 78%.
This discovery has really brought hope to children experiencing various unusual bone conditions since adults and adults suffering from osteoporosis. not only that! This finding may prove beneficial for astronauts who lost orbital bone mass. Pascale Guillot, the leader of this study, says, "The stem cells we use are excellent for protecting bones, the way the bones are much stronger and the bones are organized internally is of higher quality . "
Previous studies have proved that mesenchymal stem cells (MSC) collected in the early stages are more effective than those collected in later stages. It has several other advantages. MSCs taken earlier have the ability to expand to more numbers when needed in clinical care. They do not form tumors. They will not attack the receiver's immune system. They can move easily because they are small. Finally, because these cells are easy to reprogram, they can grow to different types of cells.
The researcher 's team was a college at the University of London who experimented with MSCs collected from amniotic fluid from pregnant women. They injected MSCs into mice with fragile bone. Another interesting discovery of the research was how the team completed the study. Nobody thinks that stem cells injected into mice will not only exert a curative effect but should also help mainly to make new bones. But this is a wrong notification. This study shows that stem cells release growth factors that stimulate bone cells and build stronger bone in a mouse model.
Gilot confirmed, "This discovery has a tremendous impact on the lives of patients with fragile bones, and there is a possibility to stop a lot of painful parts." After succeeding in studies with mice, Guyot and team hope to apply treatment for vulnerable bone disorder and osteoporosis, which affects more than 44 million patients in the United States. "This discovery has a major impact on the lives of patients with fragile bones and there is the possibility of stopping many painful fractures," Gilot said.
The team is planning to have a trial of people within the next two years. If this technology proves to be effective for human beings it may affect children in the womb and at birth. This process certainly helps them to build healthy bones. Even more interesting is that the stem cells used in this study can be transplanted from one patient to another without MSCs matching between the donor and the receiver.
